CHEMBL3341983
Ligand Summary
Name: CHEMBL3341983::US9481677, 44
PubChem: 71559365
ChEMBL: CHEMBL3341983
LyCHI: H2NUYXWBBTKD
Target Activities
SCN9A
Sodium channel protein type 9 subunit alpha
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.4 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||
IC50 | 9.4 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||
IC50 | 9.22 | Bioorg. Med. Chem. Lett., (2014) 24:16:3690 | ||||
IC50 | 9.22 | None, (2016) None:None:None | ||||
SCN1A
Sodium channel protein type 1 subunit alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.51 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||
CYP3A4
Cytochrome P450 3A4
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.11 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||
SCN5A
Sodium channel protein type 5 subunit alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.86 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||
CYP2C9
Cytochrome P450 2C9
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.77 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||
SCN2A
Sodium channel protein type 2 subunit alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.38 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||
SCN8A
Sodium channel protein type 8 subunit alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.96 | ACS Med. Chem. Lett., (2016) 7:3:277 | ||||