CHEMBL147881
Ligand Summary
Name: 2-Benzenesulfonyl-6-benzyloxy-1,2,3,4-tetrahydro-isoquinoline-1-carboxylic acid hydroxyamide
PubChem: 44364121
ChEMBL: CHEMBL147881
LyCHI: GS52MG58R1H8
Target Activities
MMP16
Matrix metalloproteinase-16
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.46 | Bioorg. Med. Chem. Lett., (2004) 14:1:47 | ||||
MMP15
Matrix metalloproteinase-15
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.77 | Bioorg. Med. Chem. Lett., (2004) 14:1:47 | ||||
MMP14
Matrix metalloproteinase-14
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.41 | Bioorg. Med. Chem. Lett., (2004) 14:1:47 | ||||
MMP2
72 kDa type IV collagenase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.62 | Bioorg. Med. Chem. Lett., (2004) 14:1:47 | ||||
MMP9
Matrix metalloproteinase-9
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.46 | Bioorg. Med. Chem. Lett., (2004) 14:1:47 | ||||
MMP12
Macrophage metalloelastase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.24 | Bioorg. Med. Chem. Lett., (2004) 14:1:47 | ||||
MMP1
Interstitial collagenase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.34 | Bioorg. Med. Chem. Lett., (2004) 14:1:47 | ||||