CHEMBL3426917
Ligand Summary
Name: 1-(2-chloro-4-([2H]-6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(5-methylisoxazol-3-yl)urea
PubChem: 118737468
ChEMBL: CHEMBL3426917
LyCHI: G8GZNMXXVXDR
Target Activities
FLT1
Vascular endothelial growth factor receptor 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.95 | Bioorg. Med. Chem. Lett., (2015) 25:11:2425 | ||||
FLT4
Vascular endothelial growth factor receptor 3
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.34 | Bioorg. Med. Chem. Lett., (2015) 25:11:2425 | ||||
PDGFRA
Platelet-derived growth factor receptor alpha
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.49 | Bioorg. Med. Chem. Lett., (2015) 25:11:2425 | ||||
KDR
Vascular endothelial growth factor receptor 2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.62 | Bioorg. Med. Chem. Lett., (2015) 25:11:2425 | ||||
EPHB2
Ephrin type-B receptor 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.57 | Bioorg. Med. Chem. Lett., (2015) 25:11:2425 | ||||