PP121
Ligand Summary
Name: PP121
PubChem: 24905142
Guide to Pharmacology: 8013
ChEMBL: CHEMBL1081312
LyCHI: G552SZUHVAF2
Target Activities
ABL1
Tyrosine-protein kinase ABL1
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.74 | |||||
IC50 | 8.7 | Nat. Chem. Biol., (2008) 4:11:691 | ||||
Ki | 7.8 | None, None:None:None | ||||
IC50 | 7.75 | Nat. Chem. Biol., (2008) 4:11:691 | ||||
IC50 | 7.75 | MedChemComm, (2012) 3:11:1337 | ||||
KDR
Vascular endothelial growth factor receptor 2
4 Activities
SRC
Proto-oncogene tyrosine-protein kinase Src
4 Activities
HCK
Tyrosine-protein kinase HCK
3 Activities
MTOR
Serine/threonine-protein kinase mTOR
3 Activities
EGFR
Epidermal growth factor receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.59 | |||||
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.28 | |||||
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.85 | |||||
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.82 | |||||
PIK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 5.96 | |||||
PDGFRA
Platelet-derived growth factor receptor alpha
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.7 | |||||
PRKDC
DNA-dependent protein kinase catalytic subunit
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.22 | |||||
RET
Proto-oncogene tyrosine-protein kinase receptor Ret
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.9 | None, None:None:None | ||||