Pharos : Ligand Details - G3WYCDXFRRD5

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: US9206139, 2

PubChem: 73603957

ChEMBL: CHEMBL4072836

LyCHI: G3WYCDXFRRD5

Target Activities

Explore Associated and Predicted Targets

ADAMTS5

Tchem

A disintegrin and metalloproteinase with thrombospondin motifs 5

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.7		None, (2015) None:None:None

IC50	8.7		J Med Chem, (2017) 60:13:5933	28613895

IC50	7.7		J Med Chem, (2017) 60:13:5933	28613895

ADAMTS4

Tchem

A disintegrin and metalloproteinase with thrombospondin motifs 4

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.7		None, (2015) None:None:None

IC50	8.7		J Med Chem, (2017) 60:13:5933	28613895

MMP12

Tchem

Macrophage metalloelastase

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.58		None, (2015) None:None:None

IC50	7.58		J Med Chem, (2017) 60:13:5933	28613895

MMP2

Tchem

72 kDa type IV collagenase

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.15		None, (2015) None:None:None

MMP9

Tchem

Matrix metalloproteinase-9

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.36		None, (2015) None:None:None

MMP1

Tchem

Interstitial collagenase

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.05		None, (2015) None:None:None