Pharos : Ligand Details - FX3GXWA1CKU1

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: AZD7325

PubChem: 23581869

Guide to Pharmacology: 7712

ChEMBL: CHEMBL1783282

LyCHI: FX3GXWA1CKU1

Target Activities

Explore Associated and Predicted Targets

GABRA2

Tclin

Gamma-aminobutyric acid receptor subunit alpha-2

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.52

Ki	9.52		J Med Chem, (2020) 63:7:3425	31738537

Ki	9.51		J Med Chem, (2020) 63:7:3425	31738537

GABRA3

Tclin

Gamma-aminobutyric acid receptor subunit alpha-3

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.89

Ki	8.89		J Med Chem, (2020) 63:7:3425	31738537

MTNR1A

Tclin

Melatonin receptor type 1A

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.9

GABRA1

Tclin

Gamma-aminobutyric acid receptor subunit alpha-1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.3		J Med Chem, (2020) 63:7:3425	31738537

GABRA5

Tclin

Gamma-aminobutyric acid receptor subunit alpha-5

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.64		J Med Chem, (2020) 63:7:3425	31738537