CHEMBL93240,CHEMBL1256737
Ligand Summary
Name: Methiothepin
PubChem: 4106
PubChem: 3039995
Guide to Pharmacology: 89
ChEMBL: CHEMBL93240
ChEMBL: CHEMBL1256737
LyCHI: FVXJVCUA3NM2
Target Activities
Items per page:
10
1 – 7 of 7
HTR7
5-hydroxytryptamine receptor 7
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.68 | Eur. J. Med. Chem., (2016) 112:None:258 | ||||
Ki | 8.43 | J. Med. Chem., (2003) 46:14:2795 | ||||
IC50 | 8.51 | Bioorg. Med. Chem., (2008) 16:5:2570 | ||||
Ki | 9.05 | J. Med. Chem., (2014) 57:11:4543 | ||||
EC50 | 9.22 | J. Nat. Prod., (2006) 69:3:432 | ||||
8.2 | ||||||
HTR6
5-hydroxytryptamine receptor 6
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.33 | Eur. J. Med. Chem., (2015) 92:None:221 | ||||
Ki | 8.39 | Eur. J. Med. Chem., (2015) 92:None:221 | ||||
Ki | 8.39 | J. Med. Chem., (2014) 57:11:4543 | ||||
IC50 | 8.62 | J. Med. Chem., (2010) 53:6:2521 | ||||
Ki | 9.4 | J. Med. Chem., (2003) 46:14:2795 | ||||
HTR5A
5-hydroxytryptamine receptor 5A
5 Activities
HTR1A
5-hydroxytryptamine receptor 1A
3 Activities
HTR2A
5-hydroxytryptamine receptor 2A
2 Activities
HTR1F
5-hydroxytryptamine receptor 1F
1 Activities
HTR2C
5-hydroxytryptamine receptor 2C
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
8.4 | ||||||