CHEMBL513147
Ligand Summary
Name: 4-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline
PubChem: 25195294
ChEMBL: CHEMBL513147
LyCHI: FJYQS2YT491M
Target Activities
ACVR1
Activin receptor type-1
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.49 | J Med Chem, (2017) 60:4:1495 | ||||
IC50 | 7.77 | Bioorg Med Chem Lett, (2018) 28:20:3356 | ||||
IC50 | 7.77 | J Med Chem, (2020) 63:9:4978 | ||||
IC50 | 7.77 | J Med Chem, (2020) 63:9:4978 | ||||
BMPR1A
Bone morphogenetic protein receptor type-1A
3 Activities
ACVRL1
Serine/threonine-protein kinase receptor R3
3 Activities
BMPR1B
Bone morphogenetic protein receptor type-1B
2 Activities
TGFBR1
TGF-beta receptor type-1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.57 | J Med Chem, (2017) 60:4:1495 | ||||
BMP4
Bone morphogenetic protein 4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.31 | Bioorg. Med. Chem. Lett., (2008) 18:15:4388 | ||||