CHEMBL4171228
Ligand Summary
Name: 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole
PubChem: 90395752
ChEMBL: CHEMBL4171228
LyCHI: FGP54K755XF5
Target Activities
BRD4
Bromodomain-containing protein 4
9 Activities
Items per page:
1 – 9 of 9
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 8.85 | J Med Chem, (2017) 60:9:3887 | ||||
Kd | 8.74 | J Med Chem, (2017) 60:9:3887 | ||||
Kd | 8.7 | J Med Chem, (2017) 60:9:3887 | ||||
IC50 | 8.14 | J Med Chem, (2017) 60:9:3887 | ||||
Ki | 8.09 | J Med Chem, (2018) 61:14:6110 | ||||
Ki | 8.09 | J Med Chem, (2017) 60:9:3887 | ||||
Kd | 8.08 | J Med Chem, (2017) 60:9:3887 | ||||
IC50 | 7.55 | J Med Chem, (2018) 61:14:6110 | ||||
IC50 | 7.55 | J Med Chem, (2017) 60:9:3887 | ||||
BRD2
Bromodomain-containing protein 2
3 Activities
BRDT
Bromodomain testis-specific protein
3 Activities
BRD3
Bromodomain-containing protein 3
3 Activities
EP300
Histone acetyltransferase p300
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.26 | J Med Chem, (2017) 60:9:3887 | ||||
CREBBP
CREB-binding protein
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 6.28 | J Med Chem, (2017) 60:9:3887 | ||||