CHEMBL3742354
Ligand Summary
Name: 1,8-Bis(pyridin-3-yl)-6-methoxy-3,4-dimethylimidazo[1,5-a]quinoxaline
PubChem: 127038509
ChEMBL: CHEMBL3742354
LyCHI: F81DKQGQXTGC
Target Activities
PDE5A
cGMP-specific 3',5'-cyclic phosphodiesterase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.63 | Eur. J. Med. Chem., (2016) 107:None:97 | ||||
PDE4A
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 6 | Eur. J. Med. Chem., (2016) 107:None:97 | ||||
PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.96 | Eur. J. Med. Chem., (2016) 107:None:97 | ||||
PDE11A
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.54 | Eur. J. Med. Chem., (2016) 107:None:97 | ||||
PDE10A
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.96 | Eur. J. Med. Chem., (2016) 107:None:97 | ||||