CHEMBL428690
Ligand Summary
Name: 2-(2-Chloro-phenyl)-5,7-dihydroxy-8-((3R,4S)-3-hydroxy-1-methyl-piperidin-4-yl)-chromen-4-one
PubChem: 5287969
Guide to Pharmacology: 5680
ChEMBL: CHEMBL428690
LyCHI: DZT8FZQTCAZT
Target Activities
Items per page:
10
1 – 8 of 8
CDK9
Cyclin-dependent kinase 9
4 Activities
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1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.7 | Nat. Chem. Biol., (2008) 4:6:357 | ||||
Kd | 8.19 | Nat. Biotechnol., (2008) 26:1:127 | ||||
Kd | 8.19 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Ki | 8.52 | J. Med. Chem., (2013) 56:3:660 | ||||
CDK4
Cyclin-dependent kinase 4
3 Activities
CDK7
Cyclin-dependent kinase 7
2 Activities
CAMKK1
Calcium/calmodulin-dependent protein kinase kinase 1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.72 | Nat. Biotechnol., (2005) 23:3:329 | ||||
PYGM
Glycogen phosphorylase, muscle form
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6 | J. Med. Chem., (2004) 47:14:3537 | ||||
CDKL5
Cyclin-dependent kinase-like 5
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.15 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
MAK
Serine/threonine-protein kinase MAK
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.55 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
ICK
Serine/threonine-protein kinase ICK
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 9.16 | Nat. Biotechnol., (2011) 29:11:1046 | ||||