CHEMBL4476621
Ligand Summary
Name: 4-(3,4-Dichlorophenyl)-1-(2-hydroxybenzoyl)-3-thiosemicarbazide
PubChem: 24424330
ChEMBL: CHEMBL4476621
LyCHI: D7FZ8A3ATNVG
Target Activities
F2
Prothrombin
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IC50 | 9.99 | Eur J Med Chem, (2018) 159:None:324 | ||||
CA2
Carbonic anhydrase 2
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IC50 | 7.54 | Eur J Med Chem, (2018) 159:None:324 | ||||
ACE
Angiotensin-converting enzyme
1 Activities
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IC50 | 9.15 | Eur J Med Chem, (2018) 159:None:324 | ||||
PTGS1
Prostaglandin G/H synthase 1
1 Activities
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IC50 | 8.1 | Eur J Med Chem, (2018) 159:None:324 | ||||
CHRM1
Muscarinic acetylcholine receptor M1
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IC50 | 7.66 | Eur J Med Chem, (2018) 159:None:324 | ||||
PPARA
Peroxisome proliferator-activated receptor alpha
1 Activities
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IC50 | 7.28 | Eur J Med Chem, (2018) 159:None:324 | ||||
HTR1A
5-hydroxytryptamine receptor 1A
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IC50 | 9.22 | Eur J Med Chem, (2018) 159:None:324 | ||||
MAOA
Amine oxidase [flavin-containing] A
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IC50 | 7.4 | Eur J Med Chem, (2018) 159:None:324 | ||||
KCNH2
Potassium voltage-gated channel subfamily H member 2
1 Activities
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IC50 | 7.1 | Eur J Med Chem, (2018) 159:None:324 | ||||
ACHE
Acetylcholinesterase
1 Activities
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IC50 | 6.28 | Eur J Med Chem, (2018) 159:None:324 | ||||
MGLL
Monoglyceride lipase
1 Activities
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IC50 | 6.44 | Eur J Med Chem, (2018) 159:None:324 | ||||
PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase A
1 Activities
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IC50 | 6.31 | Eur J Med Chem, (2018) 159:None:324 | ||||
CNR1
Cannabinoid receptor 1
1 Activities
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IC50 | 9.24 | Eur J Med Chem, (2018) 159:None:324 | ||||