RIPK1 inhibitor 22b
Ligand Summary
Name: RIPK1 inhibitor 22b
PubChem: 137321158
Guide to Pharmacology: 10155
ChEMBL: CHEMBL4281823
LyCHI: CW84PJN731N7
Target Activities
RIPK1
Receptor-interacting serine/threonine-protein kinase 1
4 Activities
MERTK
Tyrosine-protein kinase Mer
3 Activities
EIF2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1
2 Activities
FLT4
Vascular endothelial growth factor receptor 3
2 Activities
NTRK1
High affinity nerve growth factor receptor
2 Activities
NTRK2
BDNF/NT-3 growth factors receptor
2 Activities
NTRK3
NT-3 growth factor receptor
2 Activities
AXL
Tyrosine-protein kinase receptor UFO
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.46 | |||||
DDR1
Epithelial discoidin domain-containing receptor 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.46 | |||||
MAP4K5
Mitogen-activated protein kinase kinase kinase kinase 5
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.43 | |||||
RIPK3
Receptor-interacting serine/threonine-protein kinase 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 5.14 | |||||