Pharos: Illuminating the Druggable Genome

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Ligand Summary

Ligand Structure

chemical structure image

Synonyms & Links

NCATS Inxight: Drugs: 3268009

Name: 4-Methyl-piperidin-(2Z)-ylideneamine

PubChem: 3268009

ChEMBL: CHEMBL6808

LyCHI: CVJ3F9R3M8CB

Target Activities

Items per page:

10

1 – 3 of 3

NOS2

Tchem

Nitric oxide synthase, inducible

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7		J. Med. Chem., (1998) 41:1:96	9438025

IC50	7.43		Bioorg. Med. Chem. Lett., (2005) 15:8:1997	15808455

IC50	7.8		Bioorg. Med. Chem. Lett., (2000) 10:17:1975	10987430

NOS3

Tchem

Nitric oxide synthase, endothelial

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.66		Bioorg. Med. Chem. Lett., (2000) 10:17:1975	10987430

IC50	6.84		Bioorg. Med. Chem. Lett., (2005) 15:8:1997	15808455

NOS1

Tchem

Nitric oxide synthase, brain

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.7		J. Med. Chem., (1998) 41:1:96	9438025

IC50	7.8		Bioorg. Med. Chem. Lett., (2005) 15:8:1997	15808455