Ketoconazole
Ligand Summary
Target Activities
CYP3A4
Cytochrome P450 3A4
25 Activities
Items per page:
1 – 10 of 25
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.77 | J Med Chem, (2019) 62:23:10563 | ||||
IC50 | 7.74 | J Med Chem, (2019) 62:4:2083 | ||||
IC50 | 7.57 | J Med Chem, (2020) 63:14:7721 | ||||
IC50 | 7.53 | ACS Med Chem Lett, (2017) 8:8:886 | ||||
IC50 | 7.46 | Bioorg Med Chem, (2018) 26:12:3242 | ||||
IC50 | 7.44 | J Med Chem, (2020) 63:9:4837 | ||||
IC50 | 7.44 | J Med Chem, (2019) 62:3:1484 | ||||
IC50 | 7.43 | J Med Chem, (2020) 63:3:1298 | ||||
IC50 | 7.4 | J Med Chem, (2019) 62:22:10124 | ||||
IC50 | 7.25 | J Med Chem, (2019) 62:4:2083 | ||||
CYP3A5
Cytochrome P450 3A5
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.85 | J Med Chem, (2020) 63:3:1415 | ||||
IC50 | 6.79 | J Med Chem, (2020) 63:3:1415 | ||||
IC50 | 6.36 | J Med Chem, (2020) 63:3:1415 | ||||
IC50 | 6.29 | J Med Chem, (2020) 63:3:1415 | ||||
CYP19A1
Aromatase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.02 | Bioorg Med Chem, (2018) 26:8:1986 | ||||
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.32 | Bioorg Med Chem Lett, (2018) 28:13:2270 | ||||
CYP2D6
Cytochrome P450 2D6
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8 | Eur J Med Chem, (2018) 144:None:716 | ||||