Pharos : Ligand Details - CHEMBL729

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: Lopinavir

PubChem: 92727

ChEMBL: CHEMBL729

LyCHI: HKBAZ6KMX2M4

Target Activities

Explore Associated and Predicted Targets

CYP3A4

Tclin

Cytochrome P450 3A4

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	6.39		Curr. Drug Metab., (2005) 6:1:413	16248836

Ki	6		Curr. Drug Metab., (2005) 6:1:413	16248836

Ki	6		J. Med. Chem., (2012) 55:11:4896	22409598

KCNH2

Tclin

Potassium voltage-gated channel subfamily H member 2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	5.07		Eur. J. Med. Chem., (2011) 46:2:618	21185626