dapagliflozin
Ligand Summary
an Sodium-glucose cotransporter 2 (SGLT2) inhibitor, SGLT2 expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen, by inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion
UNII: 1ULL0QJ8UC
PubChem: 9887712
Guide to Pharmacology: 4594
ChEMBL: CHEMBL429910
DrugCentral: 4304
LyCHI: 2NSHZBU641RM
Target Activities
57 Activities
Items per page:
10
1 – 10 of 57
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