CHEMBL42126
Ligand Summary
NCATS Inxight: Drugs: 154575
Name: 3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide
PubChem: 154575
ChEMBL: CHEMBL42126
LyCHI: 9AKPFQRAM6ST
Target Activities
Items per page:
10
1 – 4 of 4
PDE4B
cAMP-specific 3',5'-cyclic phosphodiesterase 4B
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 8.52 | J. Med. Chem., (2007) 50:2:344 | ||||
IC50 | 8.7 | Bioorg. Med. Chem. Lett., (2010) 20:9:2928 | ||||
IC50 | 9 | J. Med. Chem., (1998) 41:3:266 | ||||
IC50 | 9.7 | Bioorg. Med. Chem. Lett., (2002) 12:4:653 | ||||
IC50 | 10.39 | Bioorg. Med. Chem., (2010) 18:6:2204 | ||||