CHEMBL3628346
Ligand Summary
Name: (S)-2-({5-[3-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]-pyrimidin-6-yl)-propyl]-thiophene-3-carbonyl}-amino)-pentanedioic Acid
PubChem: 135567035
ChEMBL: CHEMBL3628346
LyCHI: GLMZ1CWLJXB7
Target Activities
FOLR1
Folate receptor alpha
2 Activities
GART
Trifunctional purine biosynthetic protein adenosine-3
2 Activities
FOLR2
Folate receptor beta
2 Activities
SLC46A1
Proton-coupled folate transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.19 | J. Med. Chem., (2015) 58:17:6938 | ||||
SLC19A1
Folate transporter 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.72 | J. Med. Chem., (2015) 58:17:6938 | ||||