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lemborexant

Ligand Summary
Ligand Structure
Rendered image for the query structure
Description
The mechanism of action of lemborexant in the treatment of insomnia is presumed to be through antagonism of orexin receptors. The orexin neuropeptide signaling system plays a role in wakefulness. Blocking the binding of wake-promoting neuropeptides orexin A and orexin B to receptors OX1R and OX2R is thought to suppress wake drive.
Synonyms & Links
Guide to Pharmacology: 9302
DrugCentral: 5360
LyCHI:  251ZWUZ3C8HN


Target Activities