furosemide
Ligand Summary
A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY.
UNII: 7LXU5N7ZO5
PubChem: 118985385
PubChem: 3440
Guide to Pharmacology: 4839
ChEMBL: CHEMBL35
DrugCentral: 1258
LyCHI: A5RF13NLPV8J
Target Activities
SLC12A1
Solute carrier family 12 member 1
2 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
- | 5.15 | |||||
IC50 | 6.2 | INHIBITOR | ||||
SLC12A2
Solute carrier family 12 member 2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
- | 5.13 | |||||
CA7
Carbonic anhydrase 7
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.29 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA1
Carbonic anhydrase 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.21 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA2
Carbonic anhydrase 2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.19 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA12
Carbonic anhydrase 12
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.58 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA6
Carbonic anhydrase 6
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.61 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA14
Carbonic anhydrase 14
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.28 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA9
Carbonic anhydrase 9
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.38 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA4
Carbonic anhydrase 4
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.25 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA5B
Carbonic anhydrase 5B, mitochondrial
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.49 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||
CA5A
Carbonic anhydrase 5A, mitochondrial
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.3 | Bioorg. Med. Chem., (2009) 17:3:1214 | ||||