methotrexate
Ligand Summary
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
UNII: YL5FZ2Y5U1
PubChem: 126941
Guide to Pharmacology: 4815
ChEMBL: CHEMBL34259
DrugCentral: 1751
LyCHI: QBHCSP2DG8TT
Target Activities
104 Activities
Items per page:
10
1 – 10 of 104
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