ivacaftor
Ligand Summary
Ivacaftor is a potentiator of the CFTR protein. The CFTR protein is a chloride channel present at the surface of epithelial cells in multiple organs. Ivacaftor facilitates increased chloride transport by potentiating the channel-open probability (or gating) of the CFTR protein.
UNII: 1Y740ILL1Z
PubChem: 16220172
ChEMBL: CHEMBL2010601
DrugCentral: 4228
LyCHI: S91W36X1YGJK
Target Activities
8 Activities
Items per page:
10
1 – 8 of 8
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EC50 | POSITIVE MODULATOR | |||||