digoxin
Ligand Summary
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)
UNII: 73K4184T59
PubChem: 2724385
ChEMBL: CHEMBL1751
DrugCentral: 882
LyCHI: XJV4VDZHLF2C
Target Activities
10 Activities
Items per page:
10
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