pentostatin
Ligand Summary
A potent inhibitor of ADENOSINE DEAMINASE. The drug induces APOPTOSIS of LYMPHOCYTES, and is used in the treatment of many lymphoproliferative malignancies, particularly HAIRY CELL LEUKEMIA. It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
UNII: 395575MZO7
PubChem: 439693
Guide to Pharmacology: 4805
ChEMBL: CHEMBL1580
DrugCentral: 2098
LyCHI: 9YTMPRAKUUAL
Target Activities
6 Activities
Items per page:
10
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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Ki | ||||||
IC50 | INHIBITOR | |||||