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mifepristone

Ligand Summary
Ligand Structure
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Description
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Synonyms & Links
Guide to Pharmacology: 2805
DrugCentral: 1805
LyCHI:  WGH879VG45KF


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Target Activities