suvorexant
Ligand Summary
a highly selective antagonist for orexin receptors OX1R and OX2R, the orexin neuropeptide signaling system is a central promoter of wakefulness, blocking the binding of wake-promoting neuropeptides orexin A and orexin B to receptors OX1R and OX2R is thought to suppress wake drive
UNII: 081L192FO9
PubChem: 24965990
ChEMBL: CHEMBL1083659
DrugCentral: 4881
LyCHI: 2ZFRA41Q4WGJ
Target Activities
20 Activities
Items per page:
10
1 – 10 of 20
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | ||||||
Ki | ||||||
Ki | ||||||
Ki | ||||||
Ki | ||||||
Ki | ||||||
IC50 | ||||||
IC50 | ||||||
IC50 | ||||||
Ki | ||||||