progesterone
Ligand Summary
The major progestational steroid that is secreted primarily by the CORPUS LUTEUM and the PLACENTA. Progesterone acts on the UTERUS, the MAMMARY GLANDS and the BRAIN. It is required in EMBRYO IMPLANTATION; PREGNANCY maintenance, and the development of mammary tissue for MILK production. Progesterone, converted from PREGNENOLONE, also serves as an intermediate in the biosynthesis of GONADAL STEROID HORMONES and adrenal CORTICOSTEROIDS.
UNII: 4G7DS2Q64Y
PubChem: 5994
Guide to Pharmacology: 2377
ChEMBL: CHEMBL103
DrugCentral: 2279
LyCHI: MD4GF5A4W2UC
Target Activities
84 Activities
Items per page:
10
1 – 10 of 84
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
EC50 | ||||||
EC50 | ||||||
EC50 | ||||||
- | ||||||
Ki | ||||||
EC50 | ||||||
- | ||||||
Ki | ||||||
Ki | ||||||
Kd | ||||||