Pharos : Ligand Details - BYKG4VZK5QHA

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: GA

PubChem: 5288382

Guide to Pharmacology: 9829

ChEMBL: CHEMBL278315

LyCHI: BYKG4VZK5QHA

Target Activities

Explore Associated and Predicted Targets

HSP90AA1

Tchem

Heat shock protein HSP 90-alpha

20 Activities

Items per page:

1 – 10 of 20

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.85		Eur J Med Chem, (2016) 124:None:1069	27783977

IC50	7.85		Eur J Med Chem, (2018) 143:None:390	29202402

IC50	7.7		J. Med. Chem., (2008) 51:3:373	18197612

IC50	7.57		Bioorg Med Chem Lett, (2018) 28:8:1357	29545103

IC50	7.55		J. Med. Chem., (2013) 56:17:6803	23965125

IC50	7.4		Bioorg. Med. Chem. Lett., (2011) 21:8:2278	21420297

IC50	7.4		Bioorg. Med. Chem. Lett., (2011) 21:12:3627	21605975

IC50	7.4		Bioorg. Med. Chem. Lett., (2011) 21:15:4602	21715165

IC50	7.38		Bioorg Med Chem Lett, (2016) 26:17:4287	27476419

IC50	7.38		Bioorg Med Chem Lett, (2016) 26:17:4287	27476419

HSP90AB1

Tchem

Heat shock protein HSP 90-beta

8 Activities

Items per page:

1 – 8 of 8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.55			24984936

IC50	7.7		Bioorg. Med. Chem., (2009) 17:6:2225	19017562

IC50	7.66		J. Med. Chem., (2013) 56:17:6803	23965125

Kd	6.82		J. Med. Chem., (2014) 57:6:2524	24580531

Kd	6.8		J Med Chem, (2016) 59:13:6344	27312008

IC50	6.46		J. Med. Chem., (2012) 55:24:10863	23186287

Kd	6.17		J. Med. Chem., (2009) 52:10:3265	19405528

Kd	6		Bioorg. Med. Chem. Lett., (2011) 21:23:7068	22014826

TRAP1

Tchem

Heat shock protein 75 kDa, mitochondrial

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.18		J. Med. Chem., (2013) 56:17:6803	23965125