Pharos : Ligand Details - B6YF26PFMS32

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Ligand Summary

Ligand Structure

chemical structure image

Synonyms & Links

Name: 3-fluoro-4'-(pyridin-4-ylmethyl)biphenyl-4-ol

PubChem: 46901611

ChEMBL: CHEMBL1173260

LyCHI: B6YF26PFMS32

Target Activities

CYP11B1

Tclin

Cytochrome P450 11B1, mitochondrial

2 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.07		J. Med. Chem., (2010) 53:15:5749	20684610

IC50	6.46		J. Med. Chem., (2010) 53:13:5049	20550118

CYP17A1

Tclin

Steroid 17-alpha-hydroxylase/17,20 lyase

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.73		J. Med. Chem., (2010) 53:15:5749	20684610

IC50	6.73		J. Med. Chem., (2010) 53:13:5049	20550118

CYP11B2

Tchem

Cytochrome P450 11B2, mitochondrial

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.68		J. Med. Chem., (2010) 53:15:5749	20684610

IC50	6.96		J. Med. Chem., (2010) 53:13:5049	20550118

CYP3A4

Tclin

Cytochrome P450 3A4

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.05		J. Med. Chem., (2010) 53:13:5049	20550118