CHEMBL2203406
Ligand Summary
Name: N-(trans-3-(2-(((S)-2-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)(propyl)amino)ethyl)-3-hydroxycyclobutyl)-2-naphthamide
ChEMBL: CHEMBL2203406
LyCHI: 9ZZBS1HRAP53
Target Activities
DRD3
D(3) dopamine receptor
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
EC50 | 8.77 | ACS Med. Chem. Lett., (2011) 2:8:620 | ||||
Ki | 8.44 | ACS Med. Chem. Lett., (2011) 2:8:620 | ||||
Ki | 8.25 | J Med Chem, (2020) 63:10:5526 | ||||
EC50 | 8.03 | J Med Chem, (2020) 63:10:5526 | ||||
Ki | 7.52 | J Med Chem, (2020) 63:10:5526 | ||||
DRD2
D(2) dopamine receptor
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.68 | J Med Chem, (2020) 63:10:5526 | ||||
DRD4
D(4) dopamine receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.35 | J Med Chem, (2020) 63:10:5526 | ||||
SIGMAR1
Sigma non-opioid intracellular receptor 1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.28 | J Med Chem, (2020) 63:10:5526 | ||||
SLC6A4
Sodium-dependent serotonin transporter
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.5 | J Med Chem, (2020) 63:10:5526 | ||||
SLC6A3
Sodium-dependent dopamine transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.69 | J Med Chem, (2020) 63:10:5526 | ||||
SLC6A2
Sodium-dependent noradrenaline transporter
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.36 | J Med Chem, (2020) 63:10:5526 | ||||