Pharos : Ligand Details - 9XCKBG1SDLUV

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-fluoro-ethyl ester

PubChem: 11732287

ChEMBL: CHEMBL154706

LyCHI: 9XCKBG1SDLUV

Target Activities

Explore Associated and Predicted Targets

MMP3

Tchem

Stromelysin-1

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.04		J. Med. Chem., (2002) 45:4:930	11831905

Ki	8.04		Bioorg. Med. Chem. Lett., (2002) 12:4:581	11844676

MMP9

Tchem

Matrix metalloproteinase-9

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.98		J. Med. Chem., (2002) 45:4:930	11831905

Ki	7.98		Bioorg. Med. Chem. Lett., (2002) 12:4:581	11844676

MMP1

Tchem

Interstitial collagenase

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.98		J. Med. Chem., (2002) 45:4:930	11831905

Ki	7.98		Bioorg. Med. Chem. Lett., (2002) 12:4:581	11844676

ADAM17

Tchem

Disintegrin and metalloproteinase domain-containing protein 17

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.75		J. Med. Chem., (2002) 45:4:930	11831905

AREG

Tchem

Amphiregulin

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.33		J. Med. Chem., (2002) 45:4:930	11831905