Pharos : Ligand Details - 9JHJ2DHTH79U

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: Tesevatinib

ChEMBL: CHEMBL3544983

LyCHI: 9JHJ2DHTH79U

Target Activities

Explore Associated and Predicted Targets

EGFR

Tclin

Epidermal growth factor receptor

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	9.52		J Med Chem, (2019) 62:9:4772	30973735

MAPKAPK3

Tchem

MAP kinase-activated protein kinase 3

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.7		Science, (2017) 358:6367:None	29191878

EPHA7

Tchem

Ephrin type-A receptor 7

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.66		Science, (2017) 358:6367:None	29191878

BCR

Tclin

Breakpoint cluster region protein

1 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.95		Science, (2017) 358:6367:None	29191878

EPHA1

Tchem

Ephrin type-A receptor 1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8.1		Science, (2017) 358:6367:None	29191878