Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

CSNK2A1

Tchem

Casein kinase II subunit alpha

13 Activities

Items per page:

1 – 10 of 13

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	9		21174434

Ki	9.42	Eur J Med Chem, (2019) 181:None:111581	31400711

IC50	9.3	Bioorg Med Chem, (2018) 26:18:5062	30217463

Kd	9.25	Bioorg Med Chem, (2017) 25:7:2277	28274673

Kd	9.25	Bioorg Med Chem, (2017) 25:7:2277	28274673

IC50	9	J. Med. Chem., (2011) 54:2:635	21174434

IC50	9	J. Med. Chem., (2011) 54:2:635	21174434

IC50	8.7	None, (2015) None:None:None

IC50	7.85	J Med Chem, (2019) 62:4:1817	30689946

IC50	7.83	Bioorg Med Chem, (2018) 26:11:3016	29759799

CSNK2A2

Tchem

Casein kinase II subunit alpha'

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	9		21174434

Kd	9	Science, (2017) 358:6367:None	29191878

IC50	7.96	Bioorg. Med. Chem., (2016) 24:5:1136	26850376

DYRK1A

Tchem

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8.17	J Med Chem, (2018) 61:22:9791	29985601

IC50	8.17	J Med Chem, (2019) 62:4:1817	30689946

IC50	8.17	J Med Chem, (2019) 62:4:1803	30689953

CLK2

Tchem

Dual specificity protein kinase CLK2

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8.42	Bioorg Med Chem, (2018) 26:11:3016	29759799

IC50	8.4	J Med Chem, (2019) 62:4:1817	30689946

IC50	8.4	J Med Chem, (2019) 62:4:1803	30689953

DYRK1B

Tchem

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

3 Activities

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1 – 3 of 3

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8.19	J Med Chem, (2018) 61:22:9791	29985601

IC50	8.19	J Med Chem, (2019) 62:4:1817	30689946

IC50	8.19	J Med Chem, (2019) 62:4:1803	30689953

DAPK3

Tchem

Death-associated protein kinase 3

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.77		21174434

IC50	7.77	J. Med. Chem., (2011) 54:2:635	21174434

HIPK3

Tchem

Homeodomain-interacting protein kinase 3

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.35			21174434

PIM1

Tchem

Serine/threonine-protein kinase pim-1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.67			21870818

PRKAG2

Tchem

5'-AMP-activated protein kinase subunit gamma-2

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.46		Science, (2017) 358:6367:None	29191878

CLK1

Tchem

Dual specificity protein kinase CLK1

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.85		Science, (2017) 358:6367:None	29191878

CLK3

Tchem

Dual specificity protein kinase CLK3

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	8		Science, (2017) 358:6367:None	29191878

MAPKAPK3

Tchem

MAP kinase-activated protein kinase 3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	7.58		Science, (2017) 358:6367:None	29191878