CHEMBL4075917
Ligand Summary
Name: (R)-5-Fluoro-2-(5-(2-hydroxy-1-phenylethylamino)-3-(3-methyl-1H-indazol-5-yl)pyridin-2-yl)phenol
PubChem: 137651391
ChEMBL: CHEMBL4075917
LyCHI: 8VABHYBSVVFV
Target Activities
EGFR
Epidermal growth factor receptor
2 Activities
ERBB2
Receptor tyrosine-protein kinase erbB-2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9 | J Med Chem, (2017) 60:14:6018 | ||||
ABL1
Tyrosine-protein kinase ABL1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.21 | J Med Chem, (2017) 60:14:6018 | ||||
PDGFRB
Platelet-derived growth factor receptor beta
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9 | J Med Chem, (2017) 60:14:6018 | ||||
SRC
Proto-oncogene tyrosine-protein kinase Src
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.22 | J Med Chem, (2017) 60:14:6018 | ||||
KDR
Vascular endothelial growth factor receptor 2
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.59 | J Med Chem, (2017) 60:14:6018 | ||||
FGFR3
Fibroblast growth factor receptor 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.8 | J Med Chem, (2017) 60:14:6018 | ||||
FGFR1
Fibroblast growth factor receptor 1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.6 | J Med Chem, (2017) 60:14:6018 | ||||
FGFR2
Fibroblast growth factor receptor 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.33 | J Med Chem, (2017) 60:14:6018 | ||||
MERTK
Tyrosine-protein kinase Mer
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.15 | J Med Chem, (2017) 60:14:6018 | ||||
RET
Proto-oncogene tyrosine-protein kinase receptor Ret
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.4 | J Med Chem, (2017) 60:14:6018 | ||||
ERBB4
Receptor tyrosine-protein kinase erbB-4
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.62 | J Med Chem, (2017) 60:14:6018 | ||||