Pharos : Ligand Details - 8V78D7L2C384

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: 1-Imidazol-1-ylmethylxanthen-9-one

PubChem: 46867545

ChEMBL: CHEMBL1083652

LyCHI: 8V78D7L2C384

Target Activities

Explore Associated and Predicted Targets

CYP11B1

Tclin

Cytochrome P450 11B1, mitochondrial

2 Activities

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7		J. Med. Chem., (2013) 56:4:1723	23363058

IC50	7		Eur J Med Chem, (2017) 139:None:60	28797884

CYP11B2

Tchem

Cytochrome P450 11B2, mitochondrial

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.94		J. Med. Chem., (2013) 56:4:1723	23363058

IC50	6.94		Eur J Med Chem, (2017) 139:None:60	28797884

CYP19A1

Tclin

Aromatase

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.82		J. Med. Chem., (2010) 53:14:5347	20568782

CYP17A1

Tclin

Steroid 17-alpha-hydroxylase/17,20 lyase

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.06		J. Med. Chem., (2010) 53:14:5347	20568782