Pharos : Ligand Details - 8RQJGACPF8XR

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: Naringenin

PubChem: 439246

ChEMBL: CHEMBL9352

LyCHI: 8RQJGACPF8XR

Target Activities

Explore Associated and Predicted Targets

CYP19A1

Tclin

Aromatase

5 Activities

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1 – 5 of 5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	8.54		Bioorg. Med. Chem. Lett., (2010) 20:10:3050	20413308

IC50	6.64		Bioorg. Med. Chem., (2011) 19:21:6182	21978950

IC50	6.64		Bioorg. Med. Chem., (2012) 20:1:510	22115839

IC50	6.64		Bioorg. Med. Chem., (2012) 20:24:7030	23142320

IC50	6		Eur. J. Med. Chem., (2016) 119:None:141	27155469

CA7

Tclin

Carbonic anhydrase 7

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.37		Bioorg. Med. Chem., (2015) 23:22:7219	26498393

DPP4

Tclin

Dipeptidyl peptidase 4

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.62		Eur J Med Chem, (2018) 151:None:145	29609120

CA12

Tclin

Carbonic anhydrase 12

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.35		Bioorg. Med. Chem., (2015) 23:22:7219	26498393

SHBG

Tchem

Sex hormone-binding globulin

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.02		J. Med. Chem., (2008) 51:7:2047	18330978

CA4

Tclin

Carbonic anhydrase 4

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.1		Bioorg. Med. Chem., (2015) 23:22:7219	26498393