Pharos : Ligand Details - 8DTKJL33H16W

You are using an outdated browser. Please upgrade your browser to improve your experience.

Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: (-)-(S)-1',6,6',7,7'-Hexahydroxy-3,3'-dimethyl-N5-((S)-2-phenylpropyl)-N5'-((S)-2-phenylpropyl)-2,2'-binaphthyl-5,5'-dicarboxamide

PubChem: 46236926

ChEMBL: CHEMBL1094366

LyCHI: 8DTKJL33H16W

Target Activities

Explore Associated and Predicted Targets

BCL2L1

Tchem

Bcl-2-like protein 1

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Kd	6.4		J. Med. Chem., (2010) 53:10:4166	20443627

IC50	6.36		J. Med. Chem., (2010) 53:10:4166	20443627

IC50	6.19		J. Med. Chem., (2010) 53:10:4166	20443627

MCL1

Tchem

Induced myeloid leukemia cell differentiation protein Mcl-1

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.62		J. Med. Chem., (2010) 53:10:4166	20443627

IC50	6.62		J. Med. Chem., (2010) 53:10:4166	20443627

BCL2

Tclin

Apoptosis regulator Bcl-2

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.37		J. Med. Chem., (2010) 53:10:4166	20443627

IC50	6.37		J. Med. Chem., (2010) 53:10:4166	20443627

BCL2A1

Tchem

Bcl-2-related protein A1

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.12		J. Med. Chem., (2010) 53:10:4166	20443627

IC50	6.11		J. Med. Chem., (2010) 53:10:4166	20443627