CHEMBL3786012
Ligand Summary
Name: 1-(2-(2,4-difluorophenoxy)-5-(methylsulfonyl)phenyl)-3-methyl-6,7-dihydro-2H-pyrrolo[3,4-c]pyridin-4(5H)-one
PubChem: 77843982
ChEMBL: CHEMBL3786012
LyCHI: 8DD2YVTB4H6G
Target Activities
BRD4
Bromodomain-containing protein 4
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.47 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||
IC50 | 7.46 | J. Med. Chem., (2016) 59:4:1271 | ||||
Ki | 7.42 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||
EC50 | 6.54 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||
Ki | 6.52 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||
BRD2
Bromodomain-containing protein 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.57 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||
BRDT
Bromodomain testis-specific protein
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.85 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||
BRD3
Bromodomain-containing protein 3
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 6.96 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||
CREBBP
CREB-binding protein
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6 | Bioorg Med Chem Lett, (2017) 27:10:2225 | ||||