CHEMBL3922888
Ligand Summary
Name: 1-(cyclopropanesulfonyl)-4-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
PubChem: 90333640
ChEMBL: CHEMBL3922888
LyCHI: 8AGZZUNL93V8
Target Activities
CYP3A4
Cytochrome P450 3A4
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.73 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.43 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP11B1
Cytochrome P450 11B1, mitochondrial
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.24 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP21A2
Steroid 21-hydroxylase
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.55 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||