Pharos : Ligand Details

Target Activities

Explore Associated and Predicted Targets

DYRK1A

Tchem

Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.4		None, None:None:None

RPS6KA3

Tchem

Ribosomal protein S6 kinase alpha-3

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.3		None, None:None:None

DAPK3

Tchem

Death-associated protein kinase 3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.3		None, None:None:None

FLT1

Tclin

Vascular endothelial growth factor receptor 1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.2		None, None:None:None

PDGFRB

Tclin

Platelet-derived growth factor receptor beta

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.5		None, None:None:None

FLT3

Tclin

Receptor-type tyrosine-protein kinase FLT3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.6		None, None:None:None

KDR

Tclin

Vascular endothelial growth factor receptor 2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.2		None, None:None:None

JAK3

Tclin

Tyrosine-protein kinase JAK3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.7		None, None:None:None

ROCK1

Tclin

Rho-associated protein kinase 1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.4		None, None:None:None

MST1R

Tchem

Macrophage-stimulating protein receptor

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.8		None, None:None:None

GSK3A

Tclin

Glycogen synthase kinase-3 alpha

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.9		None, None:None:None

CDK7

Tchem

Cyclin-dependent kinase 7

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8		None, None:None:None

PRKCQ

Tchem

Protein kinase C theta type

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.4		None, None:None:None

IKBKE

Tchem

Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.7		None, None:None:None

PRKACA

Tchem

cAMP-dependent protein kinase catalytic subunit alpha

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.9		None, None:None:None

CLK4

Tchem

Dual specificity protein kinase CLK4

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.5		None, None:None:None

CLK2

Tchem

Dual specificity protein kinase CLK2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.1		None, None:None:None

GSK3B

Tclin

Glycogen synthase kinase-3 beta

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.6		None, None:None:None

TYRO3

Tchem

Tyrosine-protein kinase receptor TYRO3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.6		None, None:None:None

MAP4K2

Tchem

Mitogen-activated protein kinase kinase kinase kinase 2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.8		None, None:None:None

TBK1

Tchem

Serine/threonine-protein kinase TBK1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.1		None, None:None:None

DYRK1B

Tchem

Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9		None, None:None:None

NTRK3

Tclin

NT-3 growth factor receptor

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.8		None, None:None:None

LRRK2

Tchem

Leucine-rich repeat serine/threonine-protein kinase 2

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.2		None, None:None:None

MAP4K4

Tchem

Mitogen-activated protein kinase kinase kinase kinase 4

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.3		None, None:None:None

PRKAA1

Tclin

5'-AMP-activated protein kinase catalytic subunit alpha-1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.5		None, None:None:None

NTRK2

Tclin

BDNF/NT-3 growth factors receptor

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.3		None, None:None:None

RET

Tclin

Proto-oncogene tyrosine-protein kinase receptor Ret

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	8.3		None, None:None:None

PRKD3

Tchem

Serine/threonine-protein kinase D3

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	7.8		None, None:None:None

CDK5

Tchem

Cyclin-dependent-like kinase 5

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
Ki	9.2		None, None:None:None