CHEMBL194837
Ligand Summary
Name: 2-(2,4-Dichloro-phenoxy)-N-[2-(2-dimethylamino-ethoxy)-4-methyl-quinolin-6-yl]-acetamide
PubChem: 11539632
ChEMBL: CHEMBL194837
LyCHI: 844XQQS5DYWC
Target Activities
CHRM1
Muscarinic acetylcholine receptor M1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.77 | J. Med. Chem., (2005) 48:18:5684 | ||||
CHRM2
Muscarinic acetylcholine receptor M2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.35 | J. Med. Chem., (2005) 48:18:5684 | ||||
MCHR2
Melanin-concentrating hormone receptor 2
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.06 | J. Med. Chem., (2005) 48:18:5684 | ||||
HRH2
Histamine H2 receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 9.06 | J. Med. Chem., (2005) 48:18:5684 | ||||
HTR1B
5-hydroxytryptamine receptor 1B
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 9.7 | J. Med. Chem., (2005) 48:18:5684 | ||||
HTR2A
5-hydroxytryptamine receptor 2A
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 9.21 | J. Med. Chem., (2005) 48:18:5684 | ||||
DRD1
D(1A) dopamine receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.12 | J. Med. Chem., (2005) 48:18:5684 | ||||
HRH1
Histamine H1 receptor
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.46 | J. Med. Chem., (2005) 48:18:5684 | ||||
DRD3
D(3) dopamine receptor
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.89 | J. Med. Chem., (2005) 48:18:5684 | ||||
MCHR1
Melanin-concentrating hormone receptor 1
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.07 | J. Med. Chem., (2005) 48:18:5684 | ||||