Pharos : Ligand Details - 7P85HUAKZD8M

You are using an outdated browser. Please upgrade your browser to improve your experience.

Ligand Summary

Ligand Structure

chemical structure image

Synonyms & Links

Name: 4-((2S,4R)-1-Acetyl-4-((4-chlorophenyl)amino)-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl)benzoic Acid

PubChem: 52912222

ChEMBL: CHEMBL2177300

LyCHI: 7P85HUAKZD8M

Target Activities

Items per page:

10

1 – 5 of 5

BRD4

Tchem

Bromodomain-containing protein 4

7 Activities

Items per page:

1 – 7 of 7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.3		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	6.6		J. Med. Chem., (2014) 57:19:8111	25249180

Kd	7.64		J. Med. Chem., (2014) 57:19:8111	25249180

Kd	8.36		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	8.5		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	9.4		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	9.4		J. Med. Chem., (2014) 57:19:8111	25249180

BRD3

Tchem

Bromodomain-containing protein 3

6 Activities

Items per page:

1 – 6 of 6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.4		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	6.7		J. Med. Chem., (2014) 57:19:8111	25249180

Kd	7.7		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	8.7		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	9.2		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	9.6		J. Med. Chem., (2014) 57:19:8111	25249180

BRD2

Tchem

Bromodomain-containing protein 2

4 Activities

Items per page:

1 – 4 of 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.4		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	6.8		J. Med. Chem., (2014) 57:19:8111	25249180

Kd	7.6		J. Med. Chem., (2014) 57:19:8111	25249180

IC50	8.5		J. Med. Chem., (2014) 57:19:8111	25249180

PBRM1

Tchem

Protein polybromo-1

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.2		J. Med. Chem., (2014) 57:19:8111	25249180

BRDT

Tchem

Bromodomain testis-specific protein

1 Activities

Items per page:

1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.3		J. Med. Chem., (2014) 57:19:8111	25249180