Pharos : Ligand Details

Target Activities

FLT3

Tclin

Receptor-type tyrosine-protein kinase FLT3

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8.4		24044867

IC50	8.4	J. Med. Chem., (2013) 56:20:8032	24044867

LRRK2

Tchem

Leucine-rich repeat serine/threonine-protein kinase 2

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.96		24044867

IC50	7.96	J. Med. Chem., (2013) 56:20:8032	24044867

MAP3K11

Tchem

Mitogen-activated protein kinase kinase kinase 11

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.85		24044867

IC50	7.85	J. Med. Chem., (2013) 56:20:8032	24044867

MAP3K9

Tchem

Mitogen-activated protein kinase kinase kinase 9

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	7.72		24044867

IC50	7.72	J. Med. Chem., (2013) 56:20:8032	24044867

ABL1

Tclin

Tyrosine-protein kinase ABL1

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
IC50	8.52	J. Med. Chem., (2013) 56:20:8032	24044867

IC50	8.17	J. Med. Chem., (2013) 56:20:8032	24044867

DLK1

Tchem

Protein delta homolog 1

2 Activities

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1 – 2 of 2

Activity Type	Activity Value -log(M)	Activity Reference	Publications (PubMed IDs)
Kd	7.16	J. Med. Chem., (2013) 56:20:8032	24044867

IC50	6.82	J. Med. Chem., (2013) 56:20:8032	24044867

DAPK3

Tchem

Death-associated protein kinase 3

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.82			24044867

MAP3K10

Tchem

Mitogen-activated protein kinase kinase kinase 10

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	7.38			24044867

MAP3K2

Tchem

Mitogen-activated protein kinase kinase kinase 2

1 Activities

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1 – 1 of 1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
IC50	6.18			24044867