CHEMBL2431822
Ligand Summary
Name: (S)-6-(1-(6-(3,4-Difluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline
PubChem: 73293715
ChEMBL: CHEMBL2431822
LyCHI: 77J14ZJZN1MQ
Target Activities
MET
Hepatocyte growth factor receptor
2 Activities
PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase B
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.97 | J. Med. Chem., (2013) 56:17:6651 | ||||
PDE1A
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.34 | J. Med. Chem., (2013) 56:17:6651 | ||||
PDE10A
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.39 | J. Med. Chem., (2013) 56:17:6651 | ||||
PDE1C
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.02 | J. Med. Chem., (2013) 56:17:6651 | ||||