CHEMBL3980889
Ligand Summary
Name: 1-(4-{[(2S,4R)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-methanesulfonylmethanesulfonylpiperazine
PubChem: 77846873
ChEMBL: CHEMBL3980889
LyCHI: 6YYVHT1CKCXG
Target Activities
CYP3A4
Cytochrome P450 3A4
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 6.82 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP19A1
Aromatase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 6 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP17A1
Steroid 17-alpha-hydroxylase/17,20 lyase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 8.15 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP11B1
Cytochrome P450 11B1, mitochondrial
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
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IC50 | 7.17 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||
CYP21A2
Steroid 21-hydroxylase
1 Activities
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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 7.7 | Bioorg Med Chem Lett, (2016) 26:23:5825 | ||||