Pharos : Ligand Details - 6WWCYV5HDWG8

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Ligand Summary

Ligand Structure

Rendered image for the query structure

Synonyms & Links

Name: FTY720-P(R)

PubChem: 11222939

ChEMBL: CHEMBL190006

LyCHI: 6WWCYV5HDWG8

Target Activities

Explore Associated and Predicted Targets

S1PR1

Tclin

Sphingosine 1-phosphate receptor 1

5 Activities

Items per page:

1 – 5 of 5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
EC50	9.85		Bioorg. Med. Chem. Lett., (2010) 20:5:1485	20153186

IC50	9.8		Bioorg. Med. Chem. Lett., (2010) 20:5:1485	20153186

EC50	9.17		Bioorg. Med. Chem. Lett., (2007) 17:2:491	17070046

EC50	7.66		J. Med. Chem., (2005) 48:16:5373	16078855

EC50	7.63		Bioorg. Med. Chem. Lett., (2010) 20:7:2264	20188554

S1PR3

Tclin

Sphingosine 1-phosphate receptor 3

4 Activities

Items per page:

1 – 4 of 4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
EC50	8.77		Bioorg. Med. Chem. Lett., (2007) 17:2:491	17070046

EC50	8.6		Bioorg. Med. Chem. Lett., (2010) 20:5:1485	20153186

EC50	7.79		Bioorg. Med. Chem. Lett., (2010) 20:7:2264	20188554

EC50	7.54		J. Med. Chem., (2005) 48:16:5373	16078855

S1PR4

Tclin

Sphingosine 1-phosphate receptor 4

3 Activities

Items per page:

1 – 3 of 3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
EC50	9.15		Bioorg. Med. Chem. Lett., (2010) 20:5:1485	20153186

EC50	7.73		Bioorg. Med. Chem. Lett., (2007) 17:2:491	17070046

EC50	7.1		J. Med. Chem., (2005) 48:16:5373	16078855

S1PR5

Tclin

Sphingosine 1-phosphate receptor 5

2 Activities

Items per page:

1 – 2 of 2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)
EC50	9.34		Bioorg. Med. Chem. Lett., (2010) 20:5:1485	20153186

EC50	8.54		Bioorg. Med. Chem. Lett., (2007) 17:2:491	17070046