CHEMBL4080228
Ligand Summary
Name: 5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one
PubChem: 118572065
ChEMBL: CHEMBL4080228
LyCHI: 6SWA6AYN4ZZQ
Target Activities
EZH2
Histone-lysine N-methyltransferase EZH2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
IC50 | 8.4 | J Med Chem, (2018) 61:3:650 | ||||
EZH1
Histone-lysine N-methyltransferase EZH1
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Ki | 7.16 | J Med Chem, (2018) 61:3:650 | ||||