talabostat
Ligand Summary
Name: talabostat
PubChem: 6918572
Guide to Pharmacology: 9892
ChEMBL: CHEMBL67279
LyCHI: 6NP28ZC6NB6X
Target Activities
DPP4
Dipeptidyl peptidase 4
17 Activities
Items per page:
1 – 10 of 17
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 9.74 | |||||
IC50 | 10 | Bioorg. Med. Chem. Lett., (2007) 17:2:507 | ||||
Ki | 9.74 | J. Med. Chem., (2007) 50:10:2391 | ||||
Ki | 9.74 | J. Med. Chem., (2008) 51:19:6005 | ||||
IC50 | 9.05 | J. Med. Chem., (2013) 56:9:3467 | ||||
IC50 | 8.82 | J. Med. Chem., (2011) 54:7:2022 | ||||
IC50 | 8.8 | J. Med. Chem., (2007) 50:10:2391 | ||||
IC50 | 8.77 | None, (2015) None:None:None | ||||
Ki | 8.7 | Bioorg. Med. Chem. Lett., (2002) 12:20:2825 | ||||
Ki | 8.7 | J. Med. Chem., (2004) 47:17:4135 | ||||
DPP7
Dipeptidyl peptidase 2
8 Activities
Items per page:
1 – 8 of 8
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 7.82 | J. Med. Chem., (1996) 39:10:2087 | ||||
IC50 | 7.52 | Bioorg. Med. Chem. Lett., (2007) 17:2:507 | ||||
IC50 | 7.07 | Bioorg. Med. Chem. Lett., (2012) 22:10:3412 | ||||
IC50 | 7.07 | ACS Med. Chem. Lett., (2013) 4:5:491 | ||||
IC50 | 7.07 | J. Med. Chem., (2014) 57:7:3053 | ||||
IC50 | 7.07 | MedChemComm, (2014) 5:11:1700 | ||||
Ki | 6.9 | Bioorg. Med. Chem. Lett., (2002) 12:20:2825 | ||||
Ki | 6.9 | J. Med. Chem., (2004) 47:17:4135 | ||||
PREP
Prolyl endopeptidase
6 Activities
Items per page:
1 – 6 of 6
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 7.14 | J. Med. Chem., (2013) 56:9:3467 | ||||
IC50 | 6.01 | Bioorg. Med. Chem. Lett., (2012) 22:10:3412 | ||||
IC50 | 6.01 | ACS Med. Chem. Lett., (2013) 4:5:491 | ||||
IC50 | 6.01 | J. Med. Chem., (2014) 57:7:3053 | ||||
IC50 | 6.01 | MedChemComm, (2014) 5:11:1700 | ||||
IC50 | 6.01 | J Med Chem, (2019) 62:17:7874 | ||||
FAP
Prolyl endopeptidase FAP
5 Activities
Items per page:
1 – 5 of 5
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
IC50 | 7.92 | J. Med. Chem., (2013) 56:9:3467 | ||||
IC50 | 7.62 | Bioorg. Med. Chem. Lett., (2007) 17:2:507 | ||||
IC50 | 7.18 | J Med Chem, (2019) 62:17:7874 | ||||
IC50 | 7.16 | MedChemComm, (2014) 5:11:1700 | ||||
IC50 | 6.65 | Bioorg Med Chem Lett, (2020) 30:14:127253 | ||||
DPP8
Dipeptidyl peptidase 8
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 8.82 | |||||
Ki | 8.82 | J. Med. Chem., (2008) 51:19:6005 | ||||
IC50 | 8.26 | J. Med. Chem., (2013) 56:9:3467 | ||||
IC50 | 7.77 | Bioorg. Med. Chem. Lett., (2007) 17:2:507 | ||||
DPP9
Dipeptidyl peptidase 9
4 Activities
Items per page:
1 – 4 of 4
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
---|---|---|---|---|---|---|
Ki | 9.12 | |||||
Ki | 9.12 | J. Med. Chem., (2008) 51:19:6005 | ||||
IC50 | 8.7 | Bioorg. Med. Chem. Lett., (2007) 17:2:507 | ||||
IC50 | 8.66 | J. Med. Chem., (2013) 56:9:3467 | ||||