CHEMBL1908397
Ligand Summary
Name: KW-2449
PubChem: 11427553
Guide to Pharmacology: 5691
ChEMBL: CHEMBL1908397
LyCHI: 67N2T4DQ5TAN
Target Activities
Items per page:
10
1 – 10 of 19
FLT3
Receptor-type tyrosine-protein kinase FLT3
11 Activities
Items per page:
1 – 10 of 11
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.7 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 7.82 | J. Med. Chem., (2013) 56:20:8032 | ||||
Kd | 7.82 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
IC50 | 7.83 | MedChemComm, (2012) 3:1:22 | ||||
IC50 | 7.88 | MedChemComm, (2012) 3:1:22 | ||||
Kd | 7.89 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 7.89 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 7.89 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 8.18 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
IC50 | 8.18000031 | |||||
ABL1
Tyrosine-protein kinase ABL1
7 Activities
Items per page:
1 – 7 of 7
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.62 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 7.66 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 7.72 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 7.77 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 7.92 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
Kd | 8.23 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
IC50 | 7.8499999 | |||||
KIT
Mast/stem cell growth factor receptor Kit
3 Activities
MAP3K19
Mitogen-activated protein kinase kinase kinase 19
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 8.28 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
STK16
Serine/threonine-protein kinase 16
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.54 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
STK10
Serine/threonine-protein kinase 10
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.89 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
SRPK2
SRSF protein kinase 2
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.82 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
PLK4
Serine/threonine-protein kinase PLK4
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.68 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
MINK1
Misshapen-like kinase 1
1 Activities
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1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.6 | Nat. Biotechnol., (2011) 29:11:1046 | ||||
YES1
Tyrosine-protein kinase Yes
1 Activities
Items per page:
1 – 1 of 1
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) | ||
|---|---|---|---|---|---|---|
Kd | 7.75 | Nat. Biotechnol., (2011) 29:11:1046 | ||||